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PMID: 38 WheelerMBGellingRWMcIntoshCHGeorgiouJBrownJCPedersonRA

Notably, patients who underwent RYGB exhibited a significant elevation in circulating GLP-2 levels at 3 months postoperatively compared to baseline ( p = 0.02), with this difference remaining significant at 6 months ( p = 0.03)

Orlistat (Xenical/Alli), a lipase inhibitor available on the NHS, typically produces mean weight loss of around 35% compared with placebo over 12 months, making it a modest option for many patients

Clinical Drug Investigation, 36(3), 169-175