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Preparation and analyses of T21 blood samples Blood analyses were performed by Laboratorio Unico Metropolitano of Bologna (LUM) in the contest of the yearly routine follow up provided for patients with T21
On the other hand, Kupffer cell-derived IL-10 can restrict the injury by limiting iNOS induction [100, 101] and at later time points by promoting pro-regenerative gene expression in hepatocytes surrounding the area of necrosis [102]
Over time, the skin-lightening effect faded: by 6-month follow-up, only 1 out of 16 maintained visible benefit
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