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As demonstrated in our landscape analysis (Figure 3), the tirzepatide reporting profile is heavily dominated by gastrointestinal adverse events and administration-related errors, which mathematically depress the proportional reporting of cardiovascular events (Garvey et al., 2023
doi: 10.1172/jci.insight.149217 186 GermainARuppertDLevineSMHansonMR
Thus, we expect that the promotion of neurogenesis in the brain may be a key strategy to cure depression
16 Other less common potential adverse effects include gallbladder disease, pancreatitis and pancreatic cancer, thyroid cancer, acute kidney injury, and worsening of diabetic retinopathy (DRP)
Buse JB, Bain SC, Mann JFE et al
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