Vivoli E et al
Users need to focus on ensuring a good source of energy to prevent body functional issues
Our free calculator combines data from the SURMOUNT and STEP clinical trials with real-world 12-month outcomes from Second Natures medicated weight-loss programme to give you a personalised projection
Common adverse events include arthralgia (joint pain), myalgia (muscle pain), paresthesia (numbness/tingling), and injection-site reactions like redness
Acknowledgements We would like to thank J
Abbreviations SGLT-2i: Sodium-dependent glucose transporters 2 inhibitors GLP-1 Ras: Glucagon-like peptide 1 COVTs: Cardiovascular outcomes trials MACE: Major adverse cardiovascular events HHF: Hospitalization for heart failure CV death: Cardiovascular death HHF or CV death: Hospitalization for heart failure or cardiovascular death MI: Myocardial infarction T2DM: Type 2 diabetes mellitus RoB 2: Risk-of-bias tool CIs: Confidence intervals HRs: Hazard ratios References Sun H, Saeedi P, Karuranga S, Pinkepank M, Ogurtsova K, Duncan BB, Stein C, Basit A, Chan JCN, Mbanya JC, et al