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J Neurochem 67: 566593

Presented for research literature review only Cohen BE et al

Depletion of GSH and therapeutic implications The depletion of GSH levels has been demonstrated in aging and multiple chronic degenerative diseases, including neurodegenerative, cardiovascular, pulmonary, immune disorders and cancers ( For this reason, many studies have been conducted on the best methods to increase intracellular and intramitochondrial levels of GSH

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limiting alcohol enhances treatment outcomes

Neurological symptoms such as tingling or numbness are more commonly associated with B12 deficiency rather than excess and warrant medical assessment