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The dark side of GLP-1 receptor agonists primarily revolves around gastrointestinal issues, such as nausea
In addition, current studies have focused on the role of QUE combined with 5-FU in CRC and BC, but 5-FU is suitable for a variety of tumors such as GC (44) and hepatocellular carcinoma (HCC) (45)
Food supplements should not be used as a substitute for a varied diet and a healthy lifestyle
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Since genetic manipulations (e.g., knockdown, knockout, overexpression, etc.) are not possible in RBCs, pharmacological modulation of surface and intracellular proteins by specific antibodies, inhibitors, and agonists remains the only currently available approach
Exclusion criteria included a history of bariatric surgery, fundoplication, celiac disease, inflammatory bowel disease or GI cancers as well as a history of GP prior to GLP-1RA prescription
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