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Glutamate works not only as a point-to-point transmitter, but also through spill-over synaptic crosstalk between synapses in which summation of glutamate released from a neighboring synapse creates extrasynaptic signaling/volume transmission

Once opened, it should be considered contaminated and must be discarded, as refrigeration alone isnt sufficient for a multi-use vial

Benvenga S, Ruggeri RM, Russo A, Lapa D, Campenni A, Trimarchi F

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