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Conversely, the no loading dose regimen resulted in a steady increase in vitamin B12 levels from 224 to 717 pmol/L over 90 days

Yes, when prescribed and monitored by trained providers

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In 1994, the Framingham Heart Study reported the prevalence of vitamin B 12 deficiency, as defined by a serum vitamin B 12 level less than 200 pg per mL and elevated levels of serum homocysteine, methylmalonic acid, or both, to be 12 percent among 548 community-dwelling older patients