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Kim, K.-S
The ratio of active GSH to its oxidized, inactive form (GSSG) is one of the most reliable clinical biomarkers for measuring cellular oxidative stress
Semaglutide (Ozempic and Wegovy) and tirzepatide (Mounjaro and Zepbound) have experienced especially strong uptake following their FDA approvals
This aligns with the weight-independent CRP reduction seen at week 24 in SURMOUNT trials (accounting for the faster pharmacokinetic response at steady-state dosing)
Both meds can drive improved blood sugar control and potentially reduce markers of cardiovascular risk, but tolerability differs
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