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In an embryofetal development study in pregnant cynomolgus monkeys, subcutaneous doses of 0.015, 0.075 and 0.15 mg/kg twice weekly (1.9-, 9.9- and 29-fold the MRHD) were administered throughout organogenesis, from Gestation Day 16 to 50
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At this dose, appetite suppression is typically strong and consistent
10.1038/s41564-021-00880-5 Nat
In this study, tirzepatide had an average triglyceride reduction of 65% which is consistent with the literature
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