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Option 1: Discard and mix fresh Cost: Price of new vial Benefit: Guaranteed full potency Risk: None (besides cost) Option 2: Continue using Cost: None (already paid for) Benefit: Don't waste remaining peptide Risk: 10-15% potency loss means 10-15% less effectiveness Calculation: If vial costs $50 and you're at day 35 with half remaining, you're deciding whether to waste $25 to guarantee full potency, or accept 10-15% reduced effectiveness
Shaking creates foam, and foam means air-liquid interfaces where peptide molecules unfold and lose their three-dimensional structure
The samples were diluted by 100 times and measured using LCMS in the selective ion mode
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However, the researchers the trial was marked as completed, but in 2016 they cancelled submission of the results never published the results This is a red flag: we dont know if an issue or toxicity was discovered, or if it was simply a business decision
At the starting 0.25 mg/week dose, effects are usually mild
