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Threshold was set at mean background intensity, measured from three background ROIs devoid of Iba1 signal, and applied uniformly across all images using a FIJI macro to determine % of area stained for Iba1

When coverage exists, Anthem typically requires a BMI of 30 or greater, or a BMI of 27 or greater with at least one weight-related comorbidity such as type 2 diabetes, hypertension, dyslipidemia, or obstructive sleep apnea

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During the dissolution period, try not to swallow

[3] Safe administration of semaglutide requires attention to proper injection technique, dose escalation protocols, and recognition of adverse effects that may require medical attention

Infections or other medical problems can also cause changes