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JACC Advances 2025, 4: 101872

GLP-1 medications have demonstrated significant cardiovascular benefits the SELECT trial showed semaglutide reduced major cardiovascular events (heart attack, stroke, cardiovascular death) by 20% in high-risk patients

Yoshino M., Yoshino J., Kayser B.D., et al

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GPCRs are notoriously difficult to study because they are embedded in the cell membrane and often change their shape when they bind to a drug

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