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Peer review discussions suggest potential relevance for endothelial and microvascular dysfunction
The SURMOUNT-1 trial showed 22.5% average weight loss with tirzepatide versus 14.9% with semaglutide in the STEP-1 trial
Additional Trials The broader TRIUMPH program may include additional trials evaluating retatrutide in specific populations or for specific indications, such as MASLD/NASH, though detailed information about all planned studies has not been fully disclosed
MT2 is the molecule that engages all those systems
At that time, evidence was starting to appear showing semaglutide's promise for those who were clinically obese
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