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During oocyte meiosis, coordinated Ca 2+ release from the ER to mitochondria through the MAMs region is essential for Ca 2+ oscillations, which serve as key signals for cytoplasmic maturation, spindle reorganization, and chromosome alignment [64, 65]

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14 Furthermore, it has also been suggested that there can be alterations to cerebral metabolism as the virus can also cause mitochondrial dysfunction

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