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Current research directions include investigations into glutathione's potential roles in neurodegenerative disease prevention and progression, cardiovascular disease risk modification, metabolic syndrome and diabetes management, cancer prevention and potentially as adjunct to certain cancer therapies, liver disease including fatty liver and cirrhosis, respiratory conditions including COPD and asthma, autoimmune and inflammatory conditions, and healthy aging and longevity optimization

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Particularly among patients with psychiatric comorbidities, adverse neuropsychiatric outcomes such as anxiety and mood changes have been observed, especially with cannabinoid receptor 1 antagonists and stimulants [26, 27]

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Despite some breakthroughs in carnitine detection using electrochemical methods, certain methods may not directly detect carnitines in the absence of enzyme modification, potentially leading to false positive results in complex samples (Andrianova et al., 2018)