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In summary, the kinetic data for the E170X mutants support a glutaredoxin-catalysed formation of GSSEtOH as well as an exclusive interaction between Glu170 and the glutathione moiety of GSSR in accordance with the glutathione-scaffold model
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Studies in mice have shown extended lifespan and improved organ function with taurine supplementation
doi:10.1056/NEJMoa2206038
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