Given these roles, an administered dose of glycine (such as 50 mg/mL injection) may have both neuromodulatory and metabolic effects
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The peptide also reduced IL-6, IL-12, IFN-gamma, and IL-1beta mRNA levels in colonic tissue (PMC2431115)
4 Gut microbiota-derived metabolites and depression Bacterial compounds found in the gut can enter the bloodstream affect brain regions and can interact with nearby gut components like hormonal cells or neurons, which can subsequently send signals to the brain (161)