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Figure 2 Atherosclerosis, a chronic inflammatory disease, may be an ideal environment for the high viral replication capabilities of SARS-CoV-2 in human cells, enhancing hyper-inflammation secondary to immune system dysregulation (Figure 3) that leads to adverse outcomes, as shown in patients with cardiovascular risk factors

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investigated the effects of chemical triggers associated with vitiligo, specifically 4-TBP and MBEH, on MCs and observed an increase in IL-6 expression, which may contribute to the progression of autoimmune-mediated vitiligo [69]

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Castagliuolo I, Thomas Lamont J, Nikulasson ST, Pothoulakis C (1996) Saccharomyces boulardii protease inhibits Clostridium difficile toxin A effects in the rat ileum

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