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At the top, glucosinolate is hydrolyzed by myrosinase, releasing glucose and forming the unstable intermediate, glucosinolatethiohydroximate-O-sulfonate
Licorice Commonly known as glabridin, licorice is a herbal extract and contains the ingredient glycyrrhizic acid
Funding This work was supported by Sichuan Province Foundation (2021NZZJ0016), Fok Ying Tung Education Foundation (171019), and the 111 project (D17015)
When NNMT activity is inhibited, these methyl donors become available for other methylation reactions in the body
Mixing them creates stability and degradation risks that eliminate the clinical benefit of either compound
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