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Figure 1 Fatty acid metabolism encompasses long-chain, medium-chain, and short-chain fatty acid processing, with carnitine playing an indispensable role in long-chain fatty acid catabolism

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This study provides important information by demonstrating, both in vitro and in vivo in mice, that lipotoxicity alters incretin signalling via reductions in receptor levels

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We plan to investigate whether this same brain Rap1 signaling is responsible for other well-documented effects of the drug on the brain." The findings are reported in Science Advances