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Healthcare providers should evaluate and manage factors that may impede progress, including: Medications that promote weight gain (certain antidepressants, antipsychotics, corticosteroids, insulin, beta-blockers) Undiagnosed or suboptimally treated hypothyroidism Sleep disorders, particularly obstructive sleep apnoea Psychological factors including depression, anxiety, and eating disorders Social and environmental barriers to lifestyle change Patients who have not achieved expected weight loss with single-agent therapy should undergo comprehensive reassessment before considering any treatment changes
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Translating the basic knowledge of mitochondrial functions to metabolic research [PMID: 23138103] Laboratory literature summary: Translating the basic knowledge of mitochondrial functions to metabolic research protocol: role of L-carnitine
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