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In some cases, especially at the beginning of treatment for a severe deficiency, injections might be given more frequently (e.g., daily or every other day) for a short period before transitioning to a maintenance schedule

In general cyanocobalamin isn't retained as long as hydroxocobalamin so maintenance dosing tends to be more frequent - think in the states they tend to do loading doses as daily for one or two weeks followed by weekly for a few months and then monthly

Charles Brenner ( FAQs ) was asked about possible skin benefits from either taking NAD+ boosting vitamin supplement Nicotinamide Riboside NR ( FAQs ) ( Anecdotes ) or applying NR cream to your skin

For a healthy person eating meat, dairy or fortified plant foods, the NHS view is that you do not need B12 injections

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The primary forms of injectable B12 are cyanocobalamin and hydroxocobalamin, typically administered intramuscularly in the arm or thigh