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Pharmacological inhibition of SQOR with STI1 preserved cardiac function and prevented adverse remodeling

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Experimental research therefore uses GLP-RTas a model compound for studying incretin-mediated endocrine signaling and how multiple hormonal inputs interact within metabolic regulatory systems [3][5]

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Its use is limited by a broad side-effect profile, including anticholinergic effects (e.g., dry mouth, urinary retention), sedation, and orthostatic hypotension