He had been filling his prescription at a local brick-and-mortar compounding pharmacy but turned to Zappy to buy a stockpile
This is particularly noteworthy because two competing oral small-molecule GLP-1 programs from Pfizer, lotiglipron (discontinued in 2023) and danuglipron (discontinued in April 2025), were terminated due to liver toxicity concerns
Additionally, there are some compounded GLP-1 versions that contain vitamin B12 as an inactive ingredient, which isnt found in either of the commercially available drugs
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It works by mimicking a hormone called GLP-1 (glucagon-like peptide-1) that targets areas of the brain responsible for appetite and food intake
These are not clinical arguments