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Abstract Background Glutathione (GSH), a pivotal non-protein thiol, can be biosynthesized through three pathways in different organisms: (1) two consecutive enzymatic reactions catalyzed by -glutamylcysteine synthetase (Gsh1 or GshA) and glutathione synthetase (Gsh2 or GshB)
Stress and Metabolism DSIP protects against metabolic disruptions caused by stress by supporting mitochondrial oxidative phosphorylation ( 8, 9 )
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Conversely, over drugged ADCs typically exhibit higher aggregation that can be associated with increased toxicity and side effects in patients
This process is especially important in the brain, which has high energy demands and relies on efficient mitochondrial function for optimal performance
Choline plays a role in lipid transport and metabolism, working synergetically with methionine and inositol
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