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GLP-1R agonists such as semaglutide, tirzepatide, and mazdutide not only promote insulin secretion, suppress appetite, and delay gastric emptying, thereby effectively reducing body weight, but also help improve lipid profiles and reduce the risk of cardiovascular diseases

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Acknowledgements We thank Drs D.S

For some, diet and exercise may not be enough to see substantial results, particularly when factors like insulin resistance, slow metabolism, or hormonal imbalances are at play

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Funding This work was supported by the Italian Ministry of Health (RRC)