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In the sensitivity analyses, the primary outcome analysis was repeated for the PP sample, defined as participants who followed the study protocol with full adherence, attending all study visits with no substantial interruptions in treatment as monitored from the drug dose diary

Baseline characteristics and treatment effects Baseline cohort characteristics were taken from the FLOW clinical trial for the full FLOW population, as well as for the two subgroups of patients receiving and not receiving SGLT-2 inhibitors at baseline (Supplementary Material, Table S1) [22,23,24]

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Clinical studies suggest that it can reduce the risk of major adverse cardiovascular events, including heart attacks and strokes, particularly in individuals with type 2 diabetes who are at high risk for these conditions

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