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New Survey: Digestive Side Effects Cause 41% of GLP-1 Users to Suffer in Silence, Self-Adjust, or Consider Quitting Of these users, 1 in 5 believe incorrectly that GI side effects are just the price to pay, while others are quietly adjusting their own doses or stopping these popular drugs NEW YORK [July 28, 2026] A new national survey commissioned by Oshi Health and conducted by Morning Consult revealed that 75% of GLP-1 users experience a variety of digestive side effects, and that 41% are either silently enduring their symptoms, quietly adjusting medication on their own, or at risk of stopping the medication altogether
however, human studies are sparse
These osmotic laxatives draw water into the bowel, softening stools and promoting evacuation
In rare cases, a mild headache may occur if the patient is dehydrated
Q: Do temperature-related symptoms like chills or hot flashes mean something is wrong with my medication