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The total radioactivity concentrations in the intestine, skin, and lungs were similar to those in the plasma, and the mean concentrations in the gonads, myocardium, skeletal muscle, brain, and body fat were all lower than the mean concentrations in the plasma

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These free radicals damage the brain cells and can increase brain cell death

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She explains that, beyond a certain dosage, increasing the amount of the drug no longer enhances its analgesic effects