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Clinical trial NCT04050670 examined tirzepatide absorption at different sites and found something interesting
Recommendation: Test b12 immediately
The combination of semaglutide and B12 offers a complementary approach where semaglutide regulates appetite and insulin release, whereas B12 maintains nerve function, supports red blood cell production, and converts foods into cellular energy
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The doses involved are usually many times the levels the body can absorb, so most of the B12 is rapidly excreted in urine
"Vitamin and trace mineral levels after laparoscopic gastric bypass"
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