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It is designed for once-weekly subcutaneous injection

The documented considerations include mild water retention (a class effect of raising GH), injection-site reactions, occasional headache or lightheadedness, and most importantly for long-term thinking IGF-1 and sustained-GH-elevation considerations, which are why cycling with breaks is favored over indefinite use

J., Huang, H

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GLP-1 (S) and Insulin Sensitivity: A Clinical Perspective