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Yes, injection site selection does matter when administering glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), or liraglutide (Victoza, Saxenda)

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doi:10.1016/j.arr.2025.102883 55

Similar matrix remodeling effects have been observed with other regenerative peptides including BPC-157 and TB-500, though through distinct molecular mechanisms

24 In the US alone, the market generated nearly $10 billion in 2024