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Enhanced Protocol: REDEFINE Clinical Titration The clinical trial program uses a structured 16-week titration to the full therapeutic dose: This clinical protocol is the evidence-based approach used in REDEFINE trials

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Application of CYP102A1M11H as a tool for the generation of protein adducts of reactive drug metabolites

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Toxicol.Mech.Methods 2008;18(6):455-462