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Through its role in the classical JAK-STAT signaling pathway, IFN- upregulates the expression of both MHC-I and MHC-II molecules on tumor cells, increasing their susceptibility to T-cell-mediated recognition and elimination
Pharmacol Reports
10.1371/journal.pone.0001944 PLoS One
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Rodents can increase their energy expenditure via activation of brown adipose tissue (BAT)
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