Aging Cell 23 , e14102 (2024)
In human thyroid cancer, GPx3 is frequently methylated, and the expression of GPx3 is regulated by methylation of the promoter region, and this methylation is related to tumor size and lymph node metastasis through the inhibition of Wnt/-catenin signaling [100]
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This regulatory effect on the HPA axis may contribute to its anxiolytic and sleep-promoting properties
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