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Melatonin shows promise due to its anti-inflammatory/antioxidant effects, but poor bioavailability limits its use
doi:10.1038/nn.4202
Our content is regularly reviewed and updated as new clinical evidence becomes available
By blocking NNMT-mediated consumption of nicotinamide, 5-Amino-1MQ redirects nicotinamide back into the NAD+ salvage pathway
Further investigation is needed to understand the underlying mechanisms
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