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Both medicines can cause early-treatment fatigue, reflux and a general "off" feeling for a few days after a dose change

This means the medication builds up in your system over several weeks

Another limitation is the broad search strategy employed, using the terms GLP-1 and pain

Over time, this contributes to weight gain, insulin resistance, and metabolic dysfunction

Targeting gasdermin D-mediated pyroptosis: a precision anti-inflammatory strategy for acute and chronic lung diseases

A warning has also been issued to doctors to look for potential symptoms of pancreatitis in patients treated with GLP-1s, such as severe abdominal pain accompanied by nausea and vomiting