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Trying weight loss medications first before considering surgery is a reasonable approach and one many of our patients take
Weight loss over the intervention period (median 9.6 years) was 6.0% for calorie restriction and 3.5% for controls
Weight loss drugs can also slow down bile production, which is an important part of small intestine motility and food breakdown
Wegovy (the same drug at higher dose) has separate coverage criteria requiring BMI thresholds and documented lifestyle intervention failure
In contrast, while short-acting GLP-1 RAs did not show significant effects on MAKE in our cohort, it is important to note that lixisenatide has shown kidney benefits in the ELIXA trial 32
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