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Proton activation does not alter antagonist interaction with the capsaicin-binding pocket of TRPV1

In what could turn out to be one of the most remarkable scientific stories of the year, doctors in Austria, the Netherlands and the US claim to have developed a protein that can turn off senescent cells cells which contribute to the ageing process and can lead to age-related diseases like arthritis

These changes may cause thyroid hormone over-replacement and increased risk of atrial fibrillation/flutter (AF/Aflutter) and stroke

Selective NNMT inhibition as a strategy for metabolic disease

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