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1 As summarized in this review, resistance is not solely dictated by tumor-intrinsic genetic alterations but is shaped by a dynamic interplay among clonal evolution, signaling rewiring, epigenetic remodeling, altered DNA damage repair, metabolic adaptation, dysregulated cell death, TCP, microenvironmental remodeling, and hostmicrobetumor interactions

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Glutathione oxidized (400 M) inhibits epithelial sodium channel activity in primary alveolar epithelial T2 cells [2]

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