Obinutuzumab, a fully humanized type II anti-CD20 monoclonal antibody that can induce extensive B-lymphocyte depletion, has been evaluated in clinical trials for SLE, particularly focusing on LN (122)
It mimics the hormone GLP-1 (glucagon-like peptide-1), which helps regulate appetite, slow digestion, and stabilize blood sugar levels
Wintzell, E
Important: If you experience swelling of the lips, face, tongue, or throat, trouble breathing, wheezing, fainting, or widespread hives, call 911 or go to the nearest ER immediately
12.6%) and reduce cardiovascular, renal, and ocular complications in a cohort of 5000 patients per treatment (55)
95% CI, 1.06-1.14), nausea and vomiting (HR = 1.3