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However, when constipation persists despite these measures, or when it causes significant discomfort or distress, pharmacological intervention may be appropriate

With continuing developments in the field of GLP-1 RA therapy, it is important for physicians to understand the benefits and practical use of GLP-1 RAs, as well as the clinical evidence, in order to achieve positive patient outcomes

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Increasing water intake to at least 810 cups per day helps soften stool and supports the medication's effectiveness

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After subcutaneous injection, peak plasma concentrations are reached within 5-20 minutes, with an elimination half-life of approximately 10-20 minutes