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AOD-9604 is given as a subcutaneous injection, typically in the morning, on a provider-determined schedule
In the proteinprotein interaction (PPI) network, we obtained that Nrf2 regulates ferroptosis primarily by directly affecting the synthesis and function of GPX4 and the peroxisome proliferator-activated receptor gamma (PPAR) pathway, and we hypothesize that the regulation of intracellular iron concentration by Nrf2 is mainly through the Nrf2HO-1 axis
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Quick Reference: Standard Protocol Topical alternative: 0.1-1% concentration applied daily/nightly on a continuous basis
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