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Injection site reactions were observed in a minority of participants, consistent with other subcutaneous injectable weight loss medications

However, corresponding difference between CagriSema and semaglutide was not significant being -0.4 Percentage (95 Percentage CI, -0.8 to 0.0, p=0.075) [10]

The Th2 cytokines also downregulate loricrin and involucrin, two additional barrier proteins that normally create a sealed, protective envelope around skin cells