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Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
Using liquid chromatography-electrospray ionization tandem mass spectrometry, EMB has been reported to inhibit CYP1A2 and CYP2E1 strongly, CYP2C19 and CYP2D6 moderately, and CYP2A6, CYP2C9, and CYP3A4 weakly (Lee et al., 2014)
It corresponds to residues 177 through 191 of its parent sequence, with a tyrosine residue at the N-terminus in place of the phenylalanine found at position 176
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