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Both patients presented with a clinical phenotype dominated by thyroid dysfunction and low plasma selenium levels, strongly reminiscent of SECISBP2-related syndrome, though a comprehensive selenoprotein workup was not performed in either case

Unlike full-length growth hormone, which can stimulate appetite through IGF-1 production and growth hormone receptor activation, AOD-9604 does not activate the growth hormone/IGF-1 pathway

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124,125 A recent study showed that systematic administration of recombinant human PTH (134