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Furthermore, in mice treated with the combination of these drugs, there was a noteworthy decrease in SA--gal positive cells and p16 (INK4A) positive cells, indicating that AZD8055 effectively eliminated aging cells [136]

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Assuming an initial reduction of 15 % to 20 % of baseline weight, the model suggests that 4 % to 5 % of the remaining weight is lost in the long term

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