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Novaes R, Freire-de-Lima CG, de Albuquerque RC, Affonso-Mitidieri OR, Espindola O, Lima MA, de Andrada Serpa MJ, Echevarria-Lima J
For medical clinics, this change allows for a transition away from telling patients they cannot access these tools
Clear any nasal congestion: Before administering the peptide via spray, clear the nasal membrane
This stability makes it unique among therapeutic peptides and enables both injectable and oral administration routes
Putrescine serves as an immediate precursor for the other two polyamines spermidine and spermine synthesis through receiving the aminopropyl from decarboxylated S-adenosylmethionine (dcAdoMet or decSAM) by spermidine synthase (SPDSY) and spermine synthase (SPMSY), successively (Figure 1)