(2022) 23:e53746
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Ferroptosis-related proteins, Xc - anti-transport proteins, and neutral amino acid transporter proteins are available to provide T cells with the required Cys ( in vitro experiment has revealed that ferroptosis inhibitor FSP1 or GPX4 overexpression protects CD8 T cells from ferroptosis, while the utilization of GPX4 inhibitors significantly enhances the sensitivity of T cells to ferroptosis ( 4.5 Intestinal microorganisms in ferroptosis With the intensive investigation of the pathogenesis of RA, there is increasing evidence supporting the association between intestinal flora and RA
320 Similar protective roles are observed in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), where HSP70 and HSP90 suppress the aggregation of TDP-43, a protein that forms pathological cytoplasmic inclusions in affected neurons
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